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• Relationship between CYP2E1 Gene Polymorphism and Anti-tuberculosis Drug-induced Liver Injury

  Donglin Zhu, Yun Xi, Jieming Dong, Fanhua Huang, Changzhi Xu, Gang Xiao

  105-109

  
  Article ID: 289
  373  (Abstract) 168  (Download)
  

  Abstract:

   Objective: To investigate the relationship between cytochrome P450 E1 (CYP2E1) gene polymorphisms and susceptibility to anti-tuberculosis drug-induced liver damage (ATDLI) in tuberculosis patients in the Chinese Han nationality. Methods: A retrospective analysis was performed on 360 patients with tuberculosis who had liver damage after tuberculosis treatment (case group) and 360 patients with tuberculosis who did... More

  2018-11-22

• NAT2 Involed in the Susceptibility to Antituberculosis Drug-Induced Liver Injury

  Donglin Zhu, Changzhi Xu, Zhizhi Xie, Gang Xiao, Yun Xi

  6-11

  
  Article ID: 754
  227  (Abstract) 86  (Download)
  

  Abstract: Objective: To investigate whether the N-acetyltransferase 2 (NAT2) gene is involved in the development of susceptibility to antituberculosis drug-induced liver damage (ATDLI) in patients with pulmonary tuberculosis in the Han nationality. Methods: We retrospectively analyzed 300 cases of tuberculosis patients without liver damage (control group) and 221 cases of tuberculosis patients... More

  2019-07-16