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• SARS-CoV-2-the Unforeseen Peril of David Winning Against Goliath: the Immune Giant Collapsing Under Its Own Rampaging Cytokine Storm

  Xanya Sofra

  26-43

  
  Article ID: 2517
  1012  (Abstract) 114  (Download)
  

  Abstract:

  We examined SARS-CoV-2 (Covid-19) available treatments and prophylactic methods that included interventions associated with inhibiting the “type II transmembrane serine protease” (TMPRSS2) to limit the fusion between the Covid-19 Spike proteins and ACE2 receptors, or newly developed therapeutics like Remdesivir that interferes with the viral RNA replication. We explored the dilemma of ACE2 receptors that have a protective function against high blood... More

  2021-02-06

• The Danger within: Covid-19 Affinity for ACE2 Receptors in Adipose Tissue and Testes. The Protective Effects of Estradiol, Fitness, and Weight Management

  Xanya Sofra

  1-14

  
  Article ID: 2498
  1047  (Abstract) 124  (Download)
  

  Abstract:

  The imminent danger of the Covid-19 pandemic has accelerated research in pharmaceuticals that either target the viral Spike proteins fusion with ACE2 receptors, or the infectious RNA replication that often overwhelms immune defences. The scope of this review was to elucidate the main human vulnerabilities to Covid-19, including the accumulation of ACE2 receptors in testes,... More

  2021-02-06