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The imminent danger of the Covid-19 pandemic has accelerated research in pharmaceuticals that either target the viral Spike proteins fusion with ACE2 receptors, or the infectious RNA replication that often overwhelms immune defences. The scope of this review was to elucidate the main human vulnerabilities to Covid-19, including the accumulation of ACE2 receptors in testes,... More
Objective: To determine the relationship between insulin resistance and related variables (serum testosterone, interleukin (IL-6) and leptin level) in obese and non-obese healthy subjects. Methods: Community-based crosssectional, analytic study was undertaken in 60 subjects for each obese group (BMI ≥ 30.0 kg/m2) and non-obese group (BMI 18.5 to 24.9 kg/m2) (age;18-45 years) residing in Magway Township from December 2016 to December 2017.... More
We examined SARS-CoV-2 (Covid-19) available treatments and prophylactic methods that included interventions associated with inhibiting the “type II transmembrane serine protease” (TMPRSS2) to limit the fusion between the Covid-19 Spike proteins and ACE2 receptors, or newly developed therapeutics like Remdesivir that interferes with the viral RNA replication. We explored the dilemma of ACE2 receptors that have a protective function against high blood... More