Harnessing Bioengineering for Advanced Stem Cell Therapeutics: Current Progress, Challenges, and Future Horizons

Abstract

This paper examines the transformative role of bioengineering in the development of advanced stem cell therapeutics. It reviews current progress in areas such as biomaterial scaffolds, gene editing, bioprinting, and microenvironment engineering that have significantly enhanced the efficacy and precision of stem cell therapies. The paper also addresses persistent challenges, including immune compatibility, ethical concerns, and regulatory complexities that hinder widespread clinical adoption. By analyzing recent breakthroughs and case studies, we highlight how interdisciplinary approaches are accelerating the translation of stem cell research into real-world treatments. Looking ahead, we explore emerging trends, such as AI integration, personalized regenerative strategies, and next-generation biomaterials, that are poised to shape the future of stem cell therapeutics and regenerative medicine.