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• Intrahepatic Arterial Delivery of Sorafenib Eluting Beads: A Pharmacokinetics Study

  Eerdunbagena Ning, Zhijun Wang

  17-25

  
  Article ID: 1539
  914  (Abstract) 112  (Download)
  

  Abstract:

   

  Objective: To determine the slow-release effect of Sorafenib carried beads and its impact on the normal liver of dogs. Materials and Methods: (1) To obtain the maximal drug-carrying of beads, different sizes of beads (300-500 μm and 500-700 μm) were tried. Five bottles of different sizes of beads were added into 75% solution of Sorafenid-alcohol... More

  2020-05-26

• Effect of Intrahepatic Arterial Delivery of Sorafenib on Normal Liver Tissue of Rabbit: An Experimental Study

  Eerdunbagena Ning, Zhijun Wang

  1-10

  
  Article ID: 1468
  986  (Abstract) 109  (Download)
  

  Abstract:

  Objective: To assess the safety, feasibility and eluting efficiency of intrahepatic arterial delivery of sorafenib on normal liver tissue of rabbit. Methods: 24 New Zealand rabbits were randomly divided into three groups: group Ⅰ (Lipiodol-sorafenid), group Ⅱ (Lipiodol) and group Ⅲ (Sorafenib). Group Ⅰ and Ⅱ were treated by transcatheter selective hepatic arterial embolization with... More

  2020-03-30