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Found 18 items.
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Signaling Pathways Associated with Cancer Stem Cells Play a Significant Role in Immunotherapy Resistance
1-10
Article ID: 1409
299 (Abstract) 
57 (Download)
Abstract:
Cancer stem cells (CSCs) are a subpopulation of tumor cells with properties of self-renewal, pluripotency, plasticity, and differentiation, and are associated with various aberrantly stimulated signaling pathways. They are responsible for tumor recurrence, distant metastasis, and drug resistance, thus inducing poor prognosis. Immunotherapy has achieved encouraging results. However, the resistance associated with its clinical application... More
2019-12-31 -
Case Report: Granular Cell Tumor In Breast
4-6
Article ID: 1695
199 (Abstract) 44 (Download)
Abstract:
Granular cell tumor (GCT) of the breast is an unusual neoplasm, tipicallybenign, it represents between 5-6% of all GCT cases. These tumors aremore common in middle-aged premenopausal women with a greater predilection African American race [1]. Nevertheless, there are also cases described in men [2-4]. Almost all of them are favorable, the malignant casesare uncommon... More2020-04-30Postoperative Radiotherapy and N2 Non-small Cell Lung Cancer Prognosis: A Retrospective Study Based on Surveillance, Epidemiology, and End Results Database
1-7
Article ID: 3513
207 (Abstract) 55 (Download)
Abstract: The purpose of this study is to clarify the significance of postoperative radiotherapy for N2 lung cancer. This study aimed to investigate the effect of postoperative radiotherapy on the survival and prognosis of patients with N2 lung cancer. Data from 12,000 patients with N2 lung cancer were extracted from the Surveillance, Epidemiology, and End Results... More
2021-08-16Postoperative UFT-/Tegafur-based Chemotherapy Versus Postoperative Radiotherapy for Early-stage Non-small Cell Lung Cancer：A Systematic Review and Network Meta-analysis
11-18
Article ID: 1493
255 (Abstract) 43 (Download)
Abstract:
Background: Both of UFT-/Tegafur-based postoperative chemotherapy and postoperative radiotherapy have made large progress in treatment of early-stage non-small cell lung cancer. While it is unclear that, whether UFT-/Tegafur-based postoperative chemotherapy is superior to postoperative radiotherapy for early-stage non-small cell lung cancer with no direct evidence. Methods: Electronic databases (Pubmed, embase, cochrane library and clinicaltrials.gov) were searched to... More
2019-12-31The Loss of Heterozygosity of FHIT Gene in Sporadic Breast Cancer
33-39
Article ID: 3632
129 (Abstract) 53 (Download)
Abstract:
The loss of heterozygosity (LOH) is a genetic event that can change gene function. FHIT is a potential tumor suppressor gene. Although the precise FHIT molecular mechanism of action is not well understood, evidences suggest that Fhit protein reduced levels are involved in mammary carcinogenesis. The aim of this study was to investigate if FHIT LOH could influence on sporadic breast... More
2021-09-13Schistosomal Colorectal Cancer: Biomarkers and Treatment Strategies
19-23
Article ID: 1549
241 (Abstract) 61 (Download)
Abstract:
About 15.4% of human cancers worldwide have been attributed to infections. Among these, blood and liver flukes, notably Schistosoma sp, Clonorchis Sinesis, and Opisthorchis Viverrini have been associated with the development of various cancer types. Schistosoma sp. promotes colorectal cancer (CRC) progression through multiple mechanisms including production of toxins, symbiotic action with bacterial agents, and more importantly chronic inflammation. Diagnosis... More
2019-12-31High Grade Muscle-Invasive Urinary Bladder Cancer in A 36 Year Old Male Patient: A Case Report & Review of Literature
16-19
Article ID: 3866
156 (Abstract) 46 (Download)
Abstract:
We are reporting a case of urothelial bladder cancer in a 36 year old male patient with no history or exposure to any risk factors. The incidence of urothelial bladder cancer is very low in young individuals i.e. below 40 years of age with reported rate of incidence around 0.1-0.4 %. Most of the times,... More
2021-11-23Spectrum of Pediatric Malignancies: An Observational Single Center Study from Western India
Aditi Mittal
, Kanu Neemawat, Sandeep Jasuja, Anushree Chaturvedi
28-32
Article ID: 3645
163 (Abstract) 37 (Download)
Abstract: Cancer is a leading cause of death for children and adolescent worldwide. The cure rates in low middle-income countries are dismal (20%) in comparison to high income countries (80%). The first move is to assemble precise data on epidemiology of pediatric cancer across the country and its region wide variation. This study attempts to provide... More
2021-09-10Lead to Elevate the Temperature and Speed of Emergency Rescue and Nursing Care of Common Carotid Artery Rupture and Massive Hemorrhage after Operation of Typical Esophageal Cancer
36-40
Article ID: 2480
221 (Abstract) 50 (Download)
Abstract:
Objective: Objective To explore the first aid and nursing of patientswith anastomotic fistula after radical resection of esophagus carcinomacomplicated with major carotid hemorrhage. Methods: The clinical dataof anastomotic fistula complicated with carotid artery rupture and massivehemorrhage after radical resection of typical esophageal carcinoma wereanalyzed and summarized. Results: Through the close cooperation ofmedical care, the rescue... More2020-11-13Paracelsus Paradox and Drug Repurposing for Cancer
46-54
Article ID: 3649
158 (Abstract) 41 (Download)
Abstract:
Dose is one of the parameters that any pharmacologist seriously considers when studying the effects of a drug. If the necessary dose to achieve a desired pharmacological effect is in a toxic or very toxic range for human use, the drug will probably fall out from further research. The concentration that a drug can reach... More
2021-09-13Electrified Water as a Regulator of Cell Proliferation
1-10
Article ID: 2742
205 (Abstract) 69 (Download)
Abstract:
It was previously found that the electric charge of water determines its ability to interact with other substances, including biologically significant ones. It is shown here that the electric charge of water can also determine its ability to penetrate and accumulate in living cells. In particular, it has been shown that the high penetrating ability of positively charged water determines both its active... More
2021-02-10Measurement of AhR Ligands in the Tissues of Colon Cancer Patients with XRE Luciferase Reporter
3-9
Article ID: 410
322 (Abstract) 68 (Download)
Abstract:
The Aryl hydrocarbon receptor (AhR) ligands exhibiting modulating activity represents a new class of anticancer agents that can be directed towards several tumors. We have examined AhR expression in human colon cancer and adjacent non-tumor tissue. AhR expression level was about 2-7 times higher in tumor tissue samples than in the adjacent non-tumor samples (in... More
2019-07-05Associations between Body Mass Index and Breast Cancer Markers
1-7
Article ID: 2007
389 (Abstract) 60 (Download)
Abstract:
Body mass index (BMI) and breast cancer biomarkers (BCBs) such asresistin, leptin adiponectin, monocyte chemoattractant protein-1 (MCP-1)and homeostasis model assessment of insulin resistance (HOMA-IR) arehighly associated with each other. The report has focused the inter-relationship between BMI and BCBs based on probabilistic modeling. It hasbeen shown that mean BMI is directly associated with leptin (P<0.0001)and... More2020-07-03Machine Learning Algorithms for Breast Cancer Diagnosis: Challenges, Prospects and Future Research Directions
Article ID: 4977
75 (Abstract) 31 (Download)
Abstract:
Early diagnosis of breast cancer does not only increase the chances of survival but also control the diffusion of cancerous cells in the body. Previously, researchers have developed machine learning algorithms in breast cancer diagnosis such as Support Vector Machine, K-Nearest Neighbor, Convolutional Neural Network, K-means, Fuzzy C-means, Neural Network, Principle Component Analysis (PCA)... More
2022-11-02Unusual Metastases to Diaphragm and Spleen from Adenocarcinoma of Lung Detected by 18F-FDG PET/CT Imaging: A Case Report
1-3
Article ID: 1586
218 (Abstract) 55 (Download)
Abstract:
Globally, carcinoma of lung is the predominant cause of cancer deathamong both men and women. While hematogenous spread from primarylung cancer to multiple other organs is frequently reported, metastases ofmalignant tumors to diaphragm and spleen are rare. Nowadays, Positronemission tomography (PET) with 18 F- fluorodeoxyglucose (FDG) hasemerged in such a way that it has become... More2020-04-17Potential Phytochemicals for Cancer Treatment: A Review
9-15
Article ID: 3656
195 (Abstract) 57 (Download)
Abstract:
Today, cancer had been described as one of the deadliest diseases worldwide. It has been estimated that cancer causes about 9.9 million deaths in the year 2020. The conventional treatment for the disease involves single chemotherapy or a combination of mono-chemotherapy and or a combination of mono-chemotherapy and radiotherapy. However, there are negative sides... More
2021-12-07Relationship between D90 and D100 with Biochemical and Local Failure in Low-risk Prostate Cancer Treated with Low-rate Brachytherapy (LDR)
1-12
Article ID: 4721
60 (Abstract) 26 (Download)
Abstract:
Low dose rate brachytherapy (LDR) is an accepted, effective treatment with few local side effects, used as monotherapy in patients with low-risk prostate cancer (PC). The aim of this paper is to analyse 245 patients treated with LDR in the Radiation Oncology Department of the Hospital Gómez Ulla, from 2004 to 2016, evaluating the relationship... More
2022-08-19Progress in diagnosis and treatment of basal cell carcinoma
11-12
Article ID: 2038
279 (Abstract) 33 (Download)
Abstract:
Basal cell carcinoma is a common skin carcinogenesis that occurs in the epidermis and the basal layer of the skin.in general, basal cell carcinoma grows slowly, rarely metastasizes, but is locally invasive and destructive. The diagnosis is based on clinical manifestations, but the clinicopathological manifestations are different, and sometimes it is difficult to differentiate from... More
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