Unusual Metastases to Diaphragm and Spleen from Adenocarcinoma of Lung Detected by 18F-FDG PET/CT Imaging: A Case Report

Authors

  • Anindita Rani Paul Institute of Nuclear medical Physics, AERE, Savar, Dhaka-1349, Bangladesh
  • Rajib Paul Chowdhury Upazila health Complex, Bhuapur, Tangail-1960, Bangladesh
  • Pritam Saha Podder Department of Pharmacy, Jahangirnagar University, Savar-1342, Dhaka, Bangladesh
  • Umme Saoda Institute of Nuclear medical Physics, AERE, Savar, Dhaka-1349, Bangladesh

DOI:

https://doi.org/10.30564/jor.v1i3.1586

Abstract

Globally, carcinoma of lung is the predominant cause of cancer deathamong both men and women. While hematogenous spread from primarylung cancer to multiple other organs is frequently reported, metastases ofmalignant tumors to diaphragm and spleen are rare. Nowadays, Positronemission tomography (PET) with 18 F- fluorodeoxyglucose (FDG) hasemerged in such a way that it has become an effective imaging technology for the evaluation of different carcinomas, particularly for cancerstaging and follow up after therapy. PET scan is able to provide metabolicinformation. In this case, we present an attractive unified PET/CT scanimage in a patient with lung carcinoma having unusual diaphragm andsplenic metastases. So, PET/CT imaging could strongly identified rareand unusual metastatic sites of cancer and added more appropriate stagingin patient with carcinoma of lung.

Keywords:

PET/CT; Lung carcinoma; Diaphragm metastasis; Splenic metastasis

References

[1] Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA: Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc. 2008, 83: 584-594.

[2] Kara PO, Gedik GK, Sarı O, and Özbek O Rare Thyroid Cartilage and Diaphragm Metastases from Lung Cancer Visualized on F-18 FDG-PET/CT Imaging. Mol Imaging Radionucl Ther. 2011 Aug; 20(2): 70–72. DOI: 10.4274/MIRT.019882

[3] Mitsimponas N, Mitsogianni M, Crespo F, Hartmann k-A, Diederich S, Klosterhalfen B et al. Isolated Splenic Metastasis from Non-Small-Cell Lung Cancer: A Case Report and Review of the Literature.Case Rep Oncol.2017;10(2): 638–643. DOI: 10.1159/000478002

[4] Cook GJ, Fogelman I, Maisey MN. Normal physiological and benign pathological variants of 18-fluoro-2-deoxyglucose positron-emission tomography scanning: potential for error in interpretation. Semin Nucl Med. 1996, 26(4): 308–314.

[5] Bar-Shalom R, Gaitini D, Keidar Z, Israel O. Non-malignant FDG uptake in infradiaphragmatic adipose tissue: a new site of physiological tracer biodistribution characterised by PET/CT. Eur J Nucl Med Mol Imaging, 2004, 31(8): 1105–1113.

[6] Reck M, Gatzemeier U. Chemotherapy in stage-IV NSCLC. Lung Cancer. 2004, 45(Suppl 2): 217–222.

[7] Niu FY, et al. Distribution and prognosis of uncommon metastases from non-small cell lung cancer. BMC Cancer. 2016, 16: 149.DOI: 10.1186/s12885-016-2169-5

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How to Cite

Paul, A. R., Chowdhury, R. P., Podder, P. S., & Saoda, U. (2020). Unusual Metastases to Diaphragm and Spleen from Adenocarcinoma of Lung Detected by 18F-FDG PET/CT Imaging: A Case Report. Journal of Oncology Research, 1(3), 1–3. https://doi.org/10.30564/jor.v1i3.1586

Issue

Article Type

Reviews