Aloe Royal Jelly Powder Contributes to Maintain Normal Immunity: a Randomized Clinical Trial

Authors

  • Yi Yang KangAo Technology Group Co., Ltd.,
  • Chen Zhang KangAo Biotechnology (Tianjin) Co., Ltd.
  • Xiaoguang Zhu KangAo Technology Group Co., Ltd., Tianjin
  • Mei Huang KangAo Technology Group Co., Ltd.,
  • Xuemei Wang KangAo Technology Group Co., Ltd.
  • Xiaotong Liu KangAo Biotechnology (Tianjin) Co.
  • Qian Liu KangAo Biotechnology (Tianjin) Co., Ltd.
  • Fengjuan Zhang KangAo Biotechnology (Tianjin) Co., Ltd.
  • Weiwei Li KangAo Technology Group Co., Ltd.

DOI:

https://doi.org/10.30564/jams.v1i4.293

Abstract

To study the safety and the function of maintaining normal immunity of product with royal jelly lyophilized powder and whole-leaf aloe drying powder as main raw materials. Methods: Selected 125 subjects qualified for inclusion/exclusion criteria for a trial test. (The trial group lost 9 subjects. The control group lost 6 subjects.54 effective subjects of trial group includes 12 men and 42 women. 56 effective subjects of control group including 9 men and 47 women.) The trial group was evaluated by self-control and inter-group comparison, after 90 days of continuous use of aloe royal jelly. Results: There are significant differences in the overall feeling, physiological feeling, psychological feeling and comprehensive evaluation of the individuals in the trial group after 90 days (P<0.001), which are higher than before. The control group has no statistically significant difference in the comprehensive evaluation before and after the trial (P>0.05). The ratio of CD4/CD8, IgG, IgA and IgM in the trial group and the placebo control group are above the normal low-limit. There is no obvious abnormality in indicators of blood test, blood biochemistry, liver and kidney function and other clinical tests. Conclusion: Aloe royal jelly powder contributes to maintain normal immune function and has no harmful effect to the health of subjects.

References

[1] Haidong Sun, Y.S. The Nutrional Value and the Health Care Function of Royal Jelly[J]. Journal of Liaoning University, 2003, 30(2):191-194. (in Chinese)

[2] Yang, Z. Physiological Functions and Efficacy of Aloe Components[J]. Animal Husbandry and Feed Science, 2012, 33(7):8-9. (in Chinese)

[3] Samira Pourmoradian, R.M., Majid Mobasseri, Elnaz Faramarzi, Mehrnoosh Mobasseri. Effects of Royal Jelly Supplementation on Glycemic Control and Oxidative Stress Factors in Type 2 Diabetic Female: A Randomized Clinical Trial[J]. Chin J Integr Med, 2014, 20(5):347-352. (in Chinese)

[4] Yahui Li, Y.M., Kaihong Huang, Jianming Wei, Guangci Wang. Extraction of Aloe Polysaccharides by Cellulase Assisted with Ultrasonic and Studies on Antitumor Activity[J]. Journal of Chinese Institute of Food Science and Technology, 2015, 15(11):91-97. (in Chinese)

[5] Department, S. Technical Standards for Testing & Assessment of Health Food[S]. 2003:313. (in Chinese)

[6] Hongcheng Zhang, J.D., Yuming Hu. Effects of Chewable Tablets of Royal Jelly on Strengthing Immunity Functions of Mice[J]. Food Science, 2008, 29(8):579-583. (in Chinese)

[7] Kunyu Lin, L.D. Research of the royal and bee pollen extracts to enhance the mice immune ability[J]. Strait Pharmaceutical Journal, 2008, 20(6):44-47. (in Chinese)

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Issue

Vol. 1 , Iss. 4 (November 2018)

Article Type

Research Article

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