Research Article

  • Relationship between CYP2E1 Gene Polymorphism and Anti-tuberculosis Drug-induced Liver Injury

    Donglin Zhu, Yun Xi, Jieming Dong, Fanhua Huang, Changzhi Xu, Gang Xiao

    Article ID: 289
    315  (Abstract) 80  (Download)


     Objective: To investigate the relationship between cytochrome P450 E1 (CYP2E1) gene polymorphisms and susceptibility to anti-tuberculosis drug-induced liver damage (ATDLI) in tuberculosis patients in the Chinese Han nationality. Methods: A retrospective analysis was performed on 360 patients with tuberculosis who had liver damage after tuberculosis treatment (case group) and 360 patients with tuberculosis who did... More

  • Sequence Analysis of TNFRSF13b, Encoding TACI, in a Patient with Very Early Onset Inflammatory Bowel Disease: a Case Report

    Jiaying Shen

    Article ID: 290
    402  (Abstract) 65  (Download)


    Very early onset inflammatory bowel disease (VEO-IBD), IBD diagnosed before 6 years of age, frequently presents with increased severity, aggressive progression, and often poor response to conventional treatments. Although the cause of IBD is generally considered to be intestinal immune dysfunction induced by polygenic mutations and environment and other factors, VEO-IBD has a stronger genetic... More

  • Polysaccharide from Fruits of Physalis Alkekengi L. Enhances Antitumor Efficacy by a DNA Vaccine

    Yun Xi, Donglin Zhu, Jing Huang, Jingping Liu, Hua Li, Gang Xiao

    Article ID: 291
    271  (Abstract) 59  (Download)


     Physalis. alkekengi fruit has long been used in traditional Chinese medicine for tumor therapy. In the present study, using plasmids that encode ovalbumin (OVA) gene, we investigate the adjuvant activity of a polysaccharide fraction (PPSB) isolated from P.alkekengi fruit. Formulation by simple procedures of mixing of the OVA-encoding pCI-neo-sOVA plasmid with PPSB not only induced... More

  • Longevity Internal Elixir—Tradition of Yue School in East Sichuan for Warding off Disease, Keeping in Good Health and Cultivating Mind

    Grace Tan

    Article ID: 292
    277  (Abstract) 65  (Download)


    With the continuous improvement of the national economy and people’s quality of life, people’s attention to human health and health is increasing. Taking exercise and reasonable diet and good living habits to adjust the body’s meridian operation and promote the continuous optimization of human body function is an important way to achieve healthy development and... More

  • Aloe Royal Jelly Powder Contributes to Maintain Normal Immunity: a Randomized Clinical Trial

    Yi Yang, Chen Zhang, Xiaoguang Zhu, Mei Huang, Xuemei Wang, Xiaotong Liu, Qian Liu, Fengjuan Zhang, Weiwei Li

    Article ID: 293
    371  (Abstract) 57  (Download)


    To study the safety and the function of maintaining normal immunity of product with royal jelly lyophilized powder and whole-leaf aloe drying powder as main raw materials. Methods: Selected 125 subjects qualified for inclusion/exclusion criteria for a trial test. (The trial group lost 9 subjects. The control group lost 6 subjects.54 effective subjects of trial... More

  • Clinical Application of Percutaneous Transluminal Angioplasty and Stent Implantation in Acute Lower Extremity Deep Venous Thrombosis

    Lei Zhang

    Article ID: 115
    285  (Abstract) 53  (Download)


    Purpose: To analyze the application of percutaneous transluminal angioplasty and stenting in acute deep venous thrombosis of lower extremities. Methods: 70 patients were divided into two groups according to the presence or absence of percutaneous transluminal angioplasty and stenting. Results: The mean circumferential diameter difference between the affected limbs and the healthy limbs and the knees at 15... More


  • Latest Advances in the Treatment of Post-stroke Limb Spasm with Botulinum Neurotoxin

    Shuhua Chen, Lingjing Jin

    Article ID: 294
    334  (Abstract) 52  (Download)


    Objective: To describe the latest progress in the use of botulinum neurotoxin for post-stroke limb spasm. Methods: This paper looks up the relevant research literatures in recent years in PubMed, Web of Science, Springer, Ovid, CNKI, WanFang databases and summarizes them. Results: The latest progress in the use of botulinum neurotoxin for post-stroke limb spasm... More