Predisposition of Obesity through Genetic and Non-Genetic Risk Factors


  • Alice Jayapradha Cheekurthy Department of Biochemistry, Maris Stella College (Autonomous), Vijayawada-8, Andhra Pradesh, India



Globally there is an increase in the number of people affected by obesity.This has increased the count of individuals to double,triple, and even quadruple. Obesity is a complex disease that has a genetic, behavioural,socioeconomic, and environmental effect. This raises morbidity and mortality in obesity. It is an important predisposition for diabetes as well as the current pandemic COVID-19. The rationale of this case-control observational study is to identify obese individuals among the diabetic and non-diabetic population. The study includes non - genetic factors like lipid profiles with genetic factors in form of SNP as a predisposition factor. The amplified portion of the ADIPOQ gene sequence revealed the presence of SNPs rs2241767 in 46.3% population and showed increased lipid profile values. It can be concluded that these are important predisposing factors for obesity.


Obesity, Risk factor, Type 2 diabetes mellitus


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How to Cite

Cheekurthy, A. J. (2021). Predisposition of Obesity through Genetic and Non-Genetic Risk Factors. Journal of Endocrinology Research, 2(2), 27–30.


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