View Vol. 3 , Iss. 1 (January 2021)

Journal of Endocrinology Research

ISSN: 2630-5224 (Online)

Vol. 3 , Iss. 1 (January 2021)

Articles

  • Processed Radio Frequency towards Pancreas Enhancing the Deadly Diabetes Worldwide

    Md. Rahimullah Miah, Mohammad Abdul Hannan, AAM Shazzadur Rahman, Md. Shahariar Khan, Md. Mokbul Hossain, Ishrat Tasnim Rahman, Md. Sabbir Hossain, Chowdhury Shadman Shahriar, Mohammad Basir Uddin, Mohammad Taimur Hossain Talukdar, Mohammad Shamsul Alam, S.A.M. Imran Hossain, Alamgir Adil Samdany, Shahriar Hussain Chowdhury, Alexander Kiew Sayok
    1-20

    Article ID: 2826    DOI：https://doi.org/10.30564/jer.v3i1.2826

    141  (Download)

    Abstract:

    Diabetes is a chronic and debilitating disease, which is associated with a range of complications putting tremendous burden on medical, economic and socio-technological infrastructure globally. Yet the higher authorities of health services are facing the excruciating cumulative reasons of diabetes as a very imperative worldwide issue in the 21st century. The study aims to relook at the misapplication of the processed radio... More

  • Metformin and Lactic Acidosis in Diabetic Patients

    Baiyan Zhao, Zhilu Li, Zhangyi He, Xinxin Zhou, Yiying Yu, Kerong Ren, Pingping Yan
    21-26

    Article ID: 2849    DOI：https://doi.org/10.30564/jer.v3i1.2849

    77  (Download)

    Abstract:

    Metformin is the basic drug in the clinical treatment of Diabetes, often used in the treatment of Type 2 Diabetes Mellitus (T2DM).Its effect has been fully verified in the clinical treatment of T2DM. However, in the treatment of T2DM with metformin, there is still a certain probability of related lactic acidosis, and the fatality rate... More

  • Effect of Metformin on Lactate Metabolism in Normal Hepatocytes under High Glucose Stress in Vitro

    Xinxin Zhou, Xinliang Liu, Ling Zhang, Yongyan Chen, Shaoliang Guo, Yiying Yu, Zhilu Li, Pingping Yan
    27-31

    Article ID: 2864    DOI：https://doi.org/10.30564/jer.v3i1.2864

    73  (Download)

    Abstract:

    Objective To study the effect of metformin on lactate metabolism in hepatocytes in vitro under high glucose stress. In vitro LO2 cells, liver cells were randomly divided into blank control group, 25 tendency/L glucose solution, 27 tendency/L glucose solution,29 tendency/L glucose solution, 31 tendency/L glucose solution, 33 tendency/L glucose solution,35 tendency/L glucose solution treatment group, the optimal concentration of 31 tendency after... More

  • Evaluation of Genetics of Obesity and MC4R Deficiency: A Gene-oriented Approach to Obesity

    Onur Oral, George Nomikos, Nikitas Nomikos
    41-45

    Article ID: 2977    DOI：https://doi.org/10.30564/jer.v3i1.2977

    127  (Download)

    Abstract:

    Obesity is a multifactorial and complex health problem that is affected by several factors including genetic, environmental, social,behavioural, and biological aspects. Even though the influence of other environmental and behavioural factors such as sedentary lifestyle, high-calorie nutritional intake, and the inadequate expenditure of energy are acknowledged as important aspects that cause obesity, the issue... More

Review

  • Covid-19 Mutations and the Effect of Different Vaccines on Immune Memory

    Xanya Sofra
    32-40

    Article ID: 2884    DOI：https://doi.org/10.30564/jer.v3i1.2884

    87  (Download)

    Abstract:

    We traced the coronavirus classification and evolution, analyzed the Covid-19 composition and its distinguishing characteristics when compared to SARS-CoV and MERS-CoV. Despite their close kinship, SARS-CoV and Covid-19 display significant structural differences,including 380 amino acid substitutions, and variable homology between certain open reading frames that are bound to diversify the pathogenesis and virulence of the... More