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Abstract:
Obesity is a multifactorial and complex health problem that is affected by several factors including genetic, environmental, social,behavioural, and biological aspects. Even though the influence of other environmental and behavioural factors such as sedentary lifestyle, high-calorie nutritional intake, and the inadequate expenditure of energy are acknowledged as important aspects that cause obesity, the issue... More
Abstract:
We traced the coronavirus classification and evolution, analyzed the Covid-19 composition and its distinguishing characteristics when compared to SARS-CoV and MERS-CoV. Despite their close kinship, SARS-CoV and Covid-19 display significant structural differences,including 380 amino acid substitutions, and variable homology between certain open reading frames that are bound to diversify the pathogenesis and virulence of the... More
Abstract:
Objective To study the effect of metformin on lactate metabolism in hepatocytes in vitro under high glucose stress. In vitro LO2 cells, liver cells were randomly divided into blank control group, 25 tendency/L glucose solution, 27 tendency/L glucose solution,29 tendency/L glucose solution, 31 tendency/L glucose solution, 33 tendency/L glucose solution,35 tendency/L glucose solution treatment group, the optimal concentration of 31 tendency after... More
Abstract:
Metformin is the basic drug in the clinical treatment of Diabetes, often used in the treatment of Type 2 Diabetes Mellitus (T2DM).Its effect has been fully verified in the clinical treatment of T2DM. However, in the treatment of T2DM with metformin, there is still a certain probability of related lactic acidosis, and the fatality rate... More
Abstract:
Diabetes is a chronic and debilitating disease, which is associated with a range of complications putting tremendous burden on medical, economic and socio-technological infrastructure globally. Yet the higher authorities of health services are facing the excruciating cumulative reasons of diabetes as a very imperative worldwide issue in the 21st century. The study aims to relook at the misapplication of the processed radio... More