Hom Nath Chalise
Faculty Member, Department of Public Health, Nobel College affiliated to Pokhara University, Sinamangal,Kathmandu, Nepal；Vice President, Population Association of Nepal, Kathmandu Nepal
Edwin Rosenberg
Department of Sociology, Appalachian State University, Boone, North Carolina, 28608, USA
Population ageing is an issue of worldwide importance. People are living longer due to advances in education, technology, medicine, food distribution, and public health. While the COVID-19 pandemic has significant global impacts, in many countries the elderlyface threats and challenges that are unique and disproportionately severe. One such threat is that aging results in a decline in immune function, meaning elderly bodies respond more slowly and less effectively to external threats like COVID-19. Responses at individual, family, community and societal levels should take into account the heightened vulnerability of older adults during this pandemic.
[1] Chalise HN. COVID-19 situation and challenges of Nepal. Asia Pac J Public Health, 2020: 1-2. DOI:https://doi.org/10.1177/1010539520932709
[2] Chalise HN. COVID-19 situation in Nepal. Arch PsychiatrMent Health. 2020, 4: 033-034. DOI: 10.29328/journal.apmh.1001015
[3] WHO. WHO announces COVID-19 outbreak a pandemic. WHO, Geneva, Switzerland, 2020. http://www.euro.who.int/en/health-topics/health-emergencies/coronavirus-covid-19/news/news/2020/3/who-announces-covid-19-outbreak-apandemic
[4] Worldometer. COVID-19 coronavirus pandemic, USA, 2020. https://www.worldometers.info/coronavirus/?
[5] Chalise HN. South Asia is more vulnerable to COVID-19 pandemic. Arch Psychiatr Ment Health. 2020, 4: 046-047. DOI:https://doi.org/10.29328/journal.apmh.1001018
[6] Chalise HN. Aging: Basic Concept. Am J Biomed Sci& Res. 2019, 1(1). AJBSR.MS.ID.000503. DOI:https://doi.org/10.34297/AJBSR.2019.01.000503
[7] Chalise, H.N. and Rosenberg, E. Social and Health Status of Community-Dwelling Older Adults in Nepal. Advances in Aging Research, 2019, 8: 63-74. DOI:https://doi.org/10.4236/aar.2019.84005
[8] WHO. Statement - Older people are at highest risk from COVID-19, but all must act to prevent community spread, 2020. Accessed June 4, 2020 from http://www.euro.who.int/en/health-topics/health-emergencies/coronavirus-covid-19/statements/statement-older-people-are-at-highest-riskfrom-covid-19,-but-all-must-act-to-prevent-community-spread
[9] Population Reference Bureau. Countries with the oldest populations in the world, 2020. Accessed June 10, 2020 from https://www.prb.org/countries-with-the-oldest-populations
[10] Development of novel coronavirus COVID-19 case fatality rate (CFR) in China from January 19 to May 28, 2020 https://www.statista.com/statistics/1108866/china-novel-coronavirus-covid19-case-fatality-rate-development
[11] Medical News Today. The impact of the COVID-19 pandemic on older adults, Accessed at 4th June from https://www.medicalnewstoday.com/articles/the-impact-of-the-covid-19-pandemic-on-older-adults#Oldage-and-preexisting-health-conditions
[12] https://www.worldometers.info/coronavirus/coronavirus-age-sex-demographics
[13] Livingston E, Bucher K. Coronavirus Disease 2019 (COVID-19) in Italy. JAMA 2020. DOI:https://doi.org/10.1001/jama.2020.4344.32181795
[14] Chalise HN, Dhungana HN. Fears of COVID-19 catastrophe as Nepal reports death from new Coronavirus. J Phys Med RehabilDisabil, 2020, 6: 047. DOI:https://doi.org/10.24966/PMRD-8670/100047
[15] Sadighi Akha AA. Aging and the immune system: An overview. J Immunol Methods. 2018, 463: 21-26. DOI:https://doi.org/10.1016/j.jim.2018.08.005
[16] Johns Hopkins Medicine. The immune system. Accessed June 6, 2020 from https://www.hopkinsmedicine.org/health/conditions-and-diseases/the-immune-system#:~:text=The%20immune%20-system%20protects%20your,which%20you%20are%20born%20with
[17] Márquez, E.J., Chung, C., Marches, R. et al. Sexual-dimorphism in human immune system aging. Nat Commun, 2020, 11: 751. DOI:https://doi.org/10.1038/s41467-020-14396-9
[18] STAT. What explains Covid-19’s lethality for the elderly? Scientists look to ‘twilight’ of the immune system. https://www.statnews.com/2020/03/30/what-explains-coronavirus-lethality-for-elderly
[19] Montecino-Rodriguez, E., Berent-Maoz, B., Dorshkind, K. Causes, consequences, and reversal of immune system aging. The Journal of clinical investigation, 2013, 123(3): 958-965. DOI:https://doi.org/10.1172/JCI64096
Copyright © 2020 Hom Nath Chalise, Edwin Rosenberg
This is an open access article under the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) License.
Aims and Scope