Zheng yao Peng
No.1 Department of Geriatric, Hangzhou Wenzhong Hospital, Hangzhou, Zhejiang, 310000, China
Mi mi Zhou
No.1 Department of Geriatric, Hangzhou Wenzhong Hospital, Hangzhou, Zhejiang, 310000, China
Mei rong Ye
No.1 Department of Geriatric, Hangzhou Wenzhong Hospital, Hangzhou, Zhejiang, 310000, China
Yue Chen
No.1 Department of Geriatric, Hangzhou Wenzhong Hospital, Hangzhou, Zhejiang, 310000, China
What methods would you choose apart from purified protein derivative (PPD) skin test and culture for acid-fasting bacilli (AFB) to make a clinical diagnosis of pulmonary tuberculosis (TB) in an aged patient with possible TB? These are two cases of pulmonary TB, that occurred with persistent low-grade fever, fatigue and anorexia due to a mild toxemia of tuberculosis. A final diagnosis of pulmonary tuberculosis was established on the basis of mild toxemia(low-grade fever), debilitation and characteristic pulmonary CT imaging, free of PPD and interferon-gamma release assay (T-spot). The authors realized that the dosage of anti-tuberculosis drugs should be carefully controlled and the improvement of their overall nutritional status to gain better efficacy is much more needed.
[1] Seto, J., Wada, T., Suzuki, Y., et al., 2017. Mycobacterium tubereulosis transmission among elderly persons, yamagata prefecture, Japan, 2009-2015. Emerging Infectious Diseases. 23(3), 448-455.
[2] Eom, J.S., Kim, I., Kim, W.Y., et al., 2018. Household tuberculosis contact investigation in a tuberculosis-prevalent country: Are the tuberculin skin test and interferon-gamma release assay enough in elderly contacts. Medicine. 97(3), e9681
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